陈道远，男，副教授，中国药科大学学士，中山大学药物化学专业理学博士，新加坡南洋理工大学化学、化工与生物技术学院访问学者（合作导师：刑本刚教授）。主要从事多肽合成、淀粉蛋白聚集调控、抗阿尔茨海默症活性分子与荧光成像探针发现等方面工作。近5年在Mater Horiz，Phytomedicine，Spectrochim Acta A Mol Biomol Spectrosc 等重要学术刊物发表SCI论文10余篇，授权发明专利4项。主持结题国家自然科学基金青年项目1项，贵州省科技厅、贵州省卫健委、珠海市科创局等基础研究项目4项。获遵义医科大学珠海校区优秀教师、优秀共产党员等荣誉。目前担任药学专业《生物化学》课程负责人，承担研究生和本科生《生物化学》、《生物化学与分子生物学》和《医学细胞生物学》理论与实验教学，兼任《遵义医科大学学报》青年编委。通讯邮箱：1058172239@qq.com; chendaoyuan@zmuzh.edu.cn; chendy25@zmu.edu.cn.

近5年发表论文：

[1] Z. Wang, S. Peng, L. Wang, Z. Lu, Q. Wu, Y. Zhang, S. Li, D. Chen*, X. Qin* Design and Mechanistic Study of Pf-15: A Linear Antimicrobial Peptide Derived from Gramicidin S Skeleton. J Agric Food Chem. 2026;74(9):7944-7959. IF=6.2，中科院1区。

[2] Li S#, Li X#, Li S, Chen D*, Xia C*. Discovery of novel hybrids of coumarin and quinoline as potential anti-Alzheimer's disease agent. Bioorg Med Chem. 2025;133:118499. IF=3.0, 中科院3区。

[3] Tong P, Li X, Li S, Li S, Chen B*, Chen D*, Xia C*. Integrated metabolomics, transcriptomics and network pharmacology analysis to reveal the mechanisms of Danggui Buxue tang in treating Alzheimer's disease. Phytomedicine. 2025;150:157591. IF=8.3，中科院1区。

[4] Chen Q#, Li S#, Li S, Tong P, Li R, Wu J*, Xia C*, Chen D*. Rational construction of a simplified hemicyanine-based fluorescent probe CCX-1 with dual pH and viscosity response for lysosome-specific tumour imaging. Anal Methods. 2025;17(22):4533-4537. IF=2.8，中科院3区。

[5] Liu H, Li S, Li X, Li S, Wu J*, Chen D*, Xia C*. Merocyanine derivative for real-time imaging of amyloid-β and inhibition of self-aggregation and MAO-B activity. Spectrochim Acta A Mol Biomol Spectrosc. 2025;343:126582. IF=4.6，中科院2区。

[6] Guo Y, Xia C, Cao Y, Su J, Chi W*, Chen D*, Yan J*. Modulation of intramolecular freedom for tuning fluorescence imaging and photooxidation of amyloid-β aggregates. Mater Horiz. 2024;11(23):6040-6048. IF=12.8，中科院2区。

[7] Qin W#, Chen D#, Wang Y, Liu Z, Zhou B, Bu X, Wen G. Targeting the hydrophobic region of pyroglutamate-modified amyloid-β by tyrocidine A prevents its nucleation-aggregation process and its "catalytic effect" on the Aβs aggregation. J Biochem Mol Toxicol. 2024;38(8):e23800. IF=3.2，中科院3区

[8] Zhang X, Li W, Wei G, Yan Y, He R, Wang Y, Chen D*, Qin X*. A rapid-crosslinking antimicrobial hydrogel with enhanced antibacterial capabilities for improving wound healing. Front Physiol. IF=4.0, 2023;14:1206211. 中科院2区

[9] Chen D, Chen Q, Qin X, Tong P, Peng L, Zhang T, Xia C. Development and evolution of human glutaminyl cyclase inhibitors (QCIs): an alternative promising approach for disease-modifying treatment of Alzheimer's disease. Front Aging Neurosci. 2023; 15:1209863.  IF=4.8，中科院2区

[10] Wang X, Wang Y, Cao A, Luo Q, Chen D, Zhao W, Xu J, Li Q, Bu X, Quan J. Development of cyclopeptide inhibitors of cGAS targeting protein-DNA interaction and phase separation. Nat Commun. 2023;14(1):6132.  IF=16.6，中科院1区

[11] Daoyuan Chen, Haixia Sun, Binhua zhou, Guohui Wan, Xianzhang Bu*. Natural cyclopeptide as skeleton for design and discovery of protein-protein interaction modulators. 2020, The 16th Chinese international peptide Symposium. 会议论文

[12] Haixia Sun, Daoyuan Chen, Siyue Zhan, Weijian Wu, Huiying Xu, Chunxiang Luo, Hui Su, Yanqiao Feng, Weiyan Shao, Arabella Wan, Binhua Zhou, Guohui Wan, Xianzhang Bu*. Design and Discovery of Natural Cyclopeptide Skeleton Based Programmed Death Ligand 1 Inhibitor as Immune Modulator for Cancer Therapy. J Med Chem. 2020, 63(19),11286-11301. IF=6.7，中科院1区，药物化学Top期刊